eGFR / Creatinine Clearance Calculator
Medicine & Clinical ToolsEstimate creatinine clearance using the Cockcroft-Gault formula, a measure of kidney function.
Estimated Creatinine Clearance
Estimated creatinine clearance in mL per minute, using the Cockcroft-Gault formula, an indicator of kidney function used for renal drug dosing adjustments.
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Odeh AhwalBased on 3 sources
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Odeh AhwalBased on 3 sources
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Frequently Asked Questions
What does creatinine clearance measure?
Creatinine clearance estimates how efficiently the kidneys filter waste from the blood, serving as a practical proxy for glomerular filtration rate, used clinically to assess kidney function and adjust dosing of renally-cleared medications.
Why does the formula adjust for gender?
The Cockcroft-Gault formula applies a correction factor for women to account for typically lower average muscle mass, since creatinine is a byproduct of muscle metabolism and muscle mass affects baseline creatinine production.
Is this the same as eGFR reported on standard lab results?
Not exactly — many labs now report eGFR using newer formulas like CKD-EPI, which can differ somewhat from Cockcroft-Gault, though both serve the similar purpose of estimating kidney filtration function.
Sources
- Prediction of creatinine clearance from serum creatinine, PubMed (Nephron, Cockcroft & Gault, 1976)
- Cockcroft-Gault Equation for Estimating Creatinine Clearance, National Kidney Foundation
- Estimated Glomerular Filtration Rate Calculators, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK/NIH)
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