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Sodium Correction Rate Calculator (Adrogue-Madias)

Health & Fitness

Calculate the infusion rate needed to correct sodium at a safe rate, using the Adrogue-Madias formula.

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2 kg250 kg
mEq/L
100 mEq/L150 mEq/L
mEq/L
0 mEq/L600 mEq/L
mEq/L/hr
0.1 mEq/L/hr2 mEq/L/hr

Infusion Rate

55

Estimated infusion rate to achieve the aimed hourly sodium change. Educational reference only, not a substitute for clinical judgment. Standard guidance limits total daily correction to about 8 mmol/L/day.

Total Body Water

42.0

Estimated total body water.

Sodium Change per Liter Infused

9.14

Expected change in serum sodium for each liter of the chosen infusate.

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Odeh Ahwal

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Odeh Ahwal
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Frequently Asked Questions

What is the Adrogue-Madias formula used for?

It estimates how much a given IV fluid will change a patients serum sodium, and at what infusion rate, helping guide safe correction of severe hyponatremia or hypernatremia.

What is the maximum safe daily sodium correction?

Standard guidance limits total sodium correction to about 8 mmol/L per day to avoid osmotic demyelination syndrome, a serious neurological complication of overly rapid correction.

What does a common infusate sodium concentration look like?

3% saline, a commonly used hypertonic solution for severe symptomatic hyponatremia, has a sodium concentration of about 513 mEq/L, which is the default used here.

Is this calculator a substitute for medical advice?

No. This is an educational reference implementation of the Adrogue-Madias formula, not a substitute for a physicians clinical assessment. Sodium correction should always be supervised by a qualified provider with frequent lab monitoring.

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